SERUM LAYERING 101: AN ESSENTIAL GUIDE TO VISIBLE RESULTS

Understanding how skincare products work and pair together is important when it comes to achieving visible results. Like any good recipe, you need to know what to use and when to use it. This rings especially true where serums are concerned, because they are packed with active ingredients at higher concentrations than in other skincare. But while care is required, if correctly done, layering serums can transform your skin.

We’ve unpacked the basics of a great skincare routine, and created a guide to serums and product combinations to ensure real results for every complexion. Read on…

What Makes A Good Skincare Routine? 

It doesn’t have to be complicated, but an effective skincare routine does need to perform a few key functions to encourage optimal skin health:

Cleanse: It’s important to cleanse your skin daily, not only to remove makeup and sunscreen but pollutants and excess sebum, too. This reduces the risk of breakouts and premature ageing. 

Hydrate: All skin needs water-based hydration, even skin prone to breaking out, or shine. Hydration can be effectively added via serums, moisturisers, or both. 

Target: This is where serums shine! By introducing active serums into the fold, you can target personalised concerns like wrinkles, pigmentation, irritation, congestion and dullness. More on this below.

Protect: Arguably the most important aspect of any skincare routine is environmental protection, especially against UV rays. The takeaway? Wear a broad spectrum SPF every single day – rain, hail or shine. 

The Role Of Serums…

Serums typically contain a higher percentage of active ingredients, designed to help them zero in on specific concerns. Some common active ingredients – and Skinstitut favourites – include antioxidants such as Vitamin C and Niacinamide, hydrators like Hyaluronic Acid, chemical-based exfoliators, and Retinol. 

The details of serum layering depend on where you are in your skincare journey. If you’re starting out, one serum is sufficient, but for those of us looking to overhaul our complexion health, or more invested in skincare solutions, serum layering is an effective way to see real results. You can also cycle different formulas in the morning and evening, or on alternating days. Below, we unpack what to use – and when. 

What Serum Ingredients Should I Be Using? 

There’s no shortage of proven skincare ingredients out there, including the following lineup of hardworking actives we work with, and the serums you’ll find them in:

Glycolic Acid: A water-soluble Alpha-Hydroxy Acid (AHA), Glycolic Acid works to exfoliate the skin’s surface, leaving it brighter, smoother, and firmer-looking. 

Best for: Pigmentation, congestion, dullness.

Use it: A few times a week, at night. 

Formula to try: Even Blend Serum.

Hyaluronic Acid: A five-star ingredient, Hyaluronic Acid pulls water from the surrounding environment into the skin, keeping it plump, smooth and hydrated. 

Best for: Dehydration, fine lines. 

Use it: Daily, morning or evening. 

Formula to try: 1% Hyaluronic Complex Serum.

Niacinamide: Also known as Vitamin B3, this ingredient soothes and strengthens the barrier while refining skin texture. It’s also known to balance oil production. 

Best for: Discolouration, redness, irritation, breakouts. 

Use it: Daily, morning or night.

Formula to try: 10% Niacinamide Power Serum.

Retinol: Retinol is a form of Vitamin A that improves skin function and cell turnover. It’s clinically proven and a jack of all trades when it comes to complexion health. It’s safe to say we’re big Retinol fans! 

Best for: Pigmentation, wrinkles, breakouts, dullness. 

Use it: A few nights a week, gradually building up frequency to every night, or every second night.

Formula to try: Retinol Serum.  

Vitamin C, or L-Ascorbic Acid: Vitamin C is an antioxidant that protects the skin against environmental aggressors by neutralising free radicals. It’s also essential for collagen production – think of it as a glow-booster and anti-ager. The most common form used in skincare (and the most researched) is L-Ascorbic Acid. 

Best for: Pigmentation, fine lines, dullness, environmental protection. 

Use it: Daily in the morning, under your sunscreen.

Formula to try: 10% Vitamin C Super Serum.

Botanical Extracts: This broader category encompasses plant ingredients with skin-improving benefits. One of our favourites is Botanical Lanablue, a blue-green algae extract, that works as a gentle Vitamin A and Retinol alternative to deliver similar anti-ageing benefits without the associated sensitivity. 

Best for: Uneven texture, tone, and signs of ageing.

Use it: Daily, morning or evening.

Formula to try: Rejuvenate 15 Serum.  

Serum Layering Combinations We Love

When layering serums, it’s worth following a few general rules: 

  • Apply from thinnest to thickest.
  • Use the most ‘active’ formula first on clean dry skin (this includes Retinol and exfoliating acids like Glycolic Acid).
  • Follow up with nourishing or hydrating ingredients such as Hyaluronic Acid or Niacinamide.
  • One exception to this is if your skin is ultra-sensitive: if this is the case, apply hydrating or more gentle formulas first to act as a bit of a buffer.

Now, onto some high-performance serum pairings!

Morning duos: 

10% Vitamin C Power Serum + 1% Hyaluronic Complex Serum to firm, protect and hydrate.

Rejuvenate 15 Serum + 1% Hyaluronic Complex Serum to fortify, firm and smooth.

Evening duos: 

Retinol Serum + 10% Niacinamide Power Serum to firm, clarify and boost luminosity. 

Even Blend Serum + 1% Hyaluronic Complex Serum to brighten, smooth and plump. 

When To Go Pro 

Obviously, there is a disclaimer here: topical products aren’t always enough to completely resolve skin concerns. Our skin is unique and complex, and while our cosmeceutical formulas are proven to work, there’s limits to what they can achieve. 

If you want to take things up a notch, or you’re dealing with a tricky skin situation (we see you, pigmentation and acne), it’s best to consult a professional. 

We work with Laser Clinics to utilise our products in a clinical setting. Our AquaFacial is a great place to start, combining a deep cleanse, acid peel, microcurrent, and cool therapy to purify, resurface and tighten the complexion. If you want to really dial up results, this is an excellent place to start. 

Combine this pro intel on serum layering (and building a routine that works) with understanding how to glow in every season.

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TESTIMONIALS
  • Product Reviews
  • Site Reviews
05/05/2025
Jayne D.
Australia
I have been using Skinstitute over 7 years
Vitamin C Ceramide Moisturiser
05/05/2025
Lisa M.
Australia
Have been using this for a few years now and have noticed big improvements with my skin. Even friends and family have commented.
Retinol Serum
05/05/2025
Rose-Marie P.
Australia
Makes my skin feel more hydrated and evens skin tone
10% Vitamin C Super Serum
05/05/2025
Angela S.
Australia
My skin has never looked or felt better. I live for this stuff.
Expert Restore Niacinamide Replenishing Cream
04/05/2025
Jan
Australia
These products are amazing for us older ladies
Expert Restore Niacinamide Replenishing Cream
01/05/2025
Jan
Australia
Absolutely gorgeous products 😍
DELUXE NORMAL SKIN MOISTURE DEFENCE 15ML
01/05/2025
Melissa
Australia
Love this
1% Hyaluronic Complex Serum
30/04/2025
Lisa B.
Australia
Love the texture of the products and how beautiful my skin feels and looks my skin is firmer and hydrated the fine lines less obviously
Expert Reveal Retinol Face Oil
30/04/2025
Sharon K.
Australia
I love how this cream feels on the sensitive skin around my eyes and on my neck.
Ultra Firming Eye Neck Cream
26/04/2025
Ceara F.
Australia
I absolutely love Even blend serum. I use it everyday and my face glows and has a healthy hue.
Even Blend Serum
25/04/2025
Maxine A.
Australia
Wonderful love this product
Expert Reveal Retinol Face Oil
25/04/2025
Alia H.
Australia
I purchased most of the products all of them were so good I love them specially moisturiser ❤️
Moisture Defence – Normal Skin
24/04/2025
Clare H.
Australia
Great on my 50+ menopausal/combination skin. Refreshingly light, rinses well without drying.
Gentle Cleanser
17/04/2025
kellie f.
Australia
Beautiful, easy to apply, skin essential now. I am 61 - boy that sounds old! This serum sinks in quickly and works deeply. I even pop a bit on the back of my hands too! Thanks skinstitut!
1% Hyaluronic Complex Serum
15/04/2025
Janet A.
Australia
I have always struggled with skin sensitivity and redness. These are the first products that haven’t irritated my skin at all.
Age Defence SPF 50+
14/04/2025
Jacqui N.
Australia
Love how it hydrates my skin. SO many compliments on how Im looking younger. Very happy with this.
Moisture Defence – Normal Skin
13/04/2025
Ashleigh D.
Australia
I’ve seen a noticeable difference in my skin using this product, I’m less prone to breakouts and my skin is brighter and firmer.
Expert Reset Skin-Firming Peptide Serum
13/04/2025
Trudi J.
Australia
I’ve been using this product for a while and my skin has never been better. My skin looks great and feels smooth. I do get the odd compliments on how my skin is looking and feels. Highly recommend this product and all products in this range.
Expert Reset Skin-Firming Peptide Serum
13/04/2025
Helen C.
Australia
Delightful day time serum
Rejuvenate 15 Serum
12/04/2025
Tanya K.
Australia
Enjoying the product very much
Ultra Firming Eye Neck Cream
12/04/2025
Kristy C.
Australia
I’ve been using this one for about 3yrs now, beautiful thick cream but absorbs easily, no actives to burn or irritate my sensitive skin, just soothing and effective at rehydrating the wrinkles and creases!
Ultra Firming Eye Neck Cream
11/04/2025
NICOLE S.
Australia
This is the best sunscreen I've used. I always feel protected.
Age Defence SPF 50+
11/04/2025
Belinda L.
Australia
Wonderful,very quick and no fuss.
Ultra Firming Eye Neck Cream
11/04/2025
Gabriella R.
Australia
The perfect moisturiser with sunscreen, absorbs quickly is not sticky and your skin feels so hydrated afterwards. Perfect base for makeup.
Face The Day SPF 50+
11/04/2025
Brooke W.
Australia
My skin feels fantastic! I love these products and use them every day. I’ve noticed an improvement in the texture of my skin and it looks plum and glowing.
The Edit
11/04/2025
Karen g.
Australia
I love this product along with the day moisturiser.
Even Blend Serum
11/04/2025
Catherine M.
Australia
A great everyday gentle cleanser that is not too irritating on the skin. Loved all skintitut products!
Gentle Cleanser
11/04/2025
June J.
Australia
I probably could have tried a little heavier duty, but I like the way it feels on my skin. Currently going through Chemo and I want a product to help keep me hydrated.
Moisture Defence – Ultra Dry Skin
11/04/2025
Arlyn B.
Australia
There's no effect at all until now. Is like an ordinary cream that is worth 8 dollars. There are no active ingredients and cheap ingredients. I can see any difference or even a little effect. Im sorry I just telling the truth.
Expert Restore Niacinamide Replenishing Cream
04/04/2025
Lisa
Australia
Amazing product
Retinol Serum 2ml
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